Defective growth hormone secretion in children with pycnodysostosis and improved linear growth after growth hormone treatment.
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منابع مشابه
Defective growth hormone secretion in children with pycnodysostosis and improved linear growth after growth hormone treatment.
Short stature is a characteristic feature of pycnodysostosis. We report defective growth hormone secretion in response to provocation and low insulin-like growth factor-I (IGF-I) concentration in five out of six patients with pycnodysostosis. Physiological replacement with growth hormone increased IGF-I concentration and improved linear growth in these children.
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1996
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.75.3.242